The announcement came as the tech giant revealed they would be creating 2,000 jobs across the UK as a whole, taking their total British workforce to almost 30,000.
The Amazon Development Centre Scotland, located on Waterloo Place, is responsible for "devising and growing innovations for Amazon around the world".
There teams of developers, designers and leaders run parts of the business and technology operations.
Development centres in the Scottish capital, London and Cambridge will see the creation of at least 170 new jobs, while the new corporate office in Manchester is also hiring.
The firm said they would create high-skilled positions for engineers, software developers, data scientists and cloud and machine learning experts.
Amazon UK country manager Doug Gurr said: "The UK is a fantastic hub for global talent and the exciting, innovative work that takes place here benefits Amazon's customers around the world.
"Whether you are looking for a highly specialised role at one of our fulfilment centres or in a field such as machine learning or flight engineering, we offer a wide variety of opportunities."
Last year Amazon created 2500 new jobs and in 2017 the opening of a new head office helped add 5,000 roles. The newest announcement is in addition to their commitment to create more than 1000 new UK apprenticeships over the next two years...